{"id":7712,"date":"2022-11-25T12:52:39","date_gmt":"2022-11-25T11:52:39","guid":{"rendered":"https:\/\/www.ezn.de\/ezn-patent\/kristallines-hybridschicht-dicalciumphosphat-hlcp-herstellverfahren-und-anwendung\/"},"modified":"2022-11-28T13:45:53","modified_gmt":"2022-11-28T12:45:53","slug":"kristallines-hybridschicht-dicalciumphosphat-hlcp-herstellverfahren-und-anwendung","status":"publish","type":"ezn-patent","link":"https:\/\/www.ezn.de\/en\/ezn-patent\/kristallines-hybridschicht-dicalciumphosphat-hlcp-herstellverfahren-und-anwendung\/","title":{"rendered":"Crystalline hybrid layer dicalcium phosphate (HLCP), production process and application"},"content":{"rendered":"

Despite the broad potential and scope of application in bone tissue engineering, conventional CaP materials exhibit poor biodegradability, low load-bearing capacity, modest mechanical properties, and insufficient bioactivity or osteoinductivity, among others. These properties are detrimental to targeted drug delivery and sustained action and\/or controlled drug release. Porous CaP materials are useful for cell colonization, vascularization, bone formation, and drug and nutrient diffusion. However, superior mechanical properties needed for many medical applications require strong and dense materials. Therefore, in the development of new CaP materials, a balance between high drug loading (only achievable via porosity in current materials) and mechanical properties is of key importance, along with good biocompatibility and activity.<\/p>\n","protected":false},"excerpt":{"rendered":"

Despite the broad potential and scope of application in bone tissue engineering, conventional CaP materials exhibit poor biodegradability, low load-bearing capacity, modest mechanical properties, and insufficient bioactivity or osteoinductivity, among others. These properties are detrimental to targeted drug delivery and sustained action and\/or controlled drug release. Porous CaP materials are useful for cell colonization, vascularization, […]<\/p>\n","protected":false},"author":1,"featured_media":0,"menu_order":0,"template":"","meta":{"footnotes":""},"ezn-category":[3367,2433,2403,2438],"yoast_head":"\nCrystalline hybrid layer dicalcium phosphate (HLCP), production process and application | EZN<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ezn.de\/en\/ezn-patent\/kristallines-hybridschicht-dicalciumphosphat-hlcp-herstellverfahren-und-anwendung\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Crystalline hybrid layer dicalcium phosphate (HLCP), production process and application | EZN\" \/>\n<meta property=\"og:description\" content=\"Despite the broad potential and scope of application in bone tissue engineering, conventional CaP materials exhibit poor biodegradability, low load-bearing capacity, modest mechanical properties, and insufficient bioactivity or osteoinductivity, among others. These properties are detrimental to targeted drug delivery and sustained action and\/or controlled drug release. Porous CaP materials are useful for cell colonization, vascularization, […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.ezn.de\/en\/ezn-patent\/kristallines-hybridschicht-dicalciumphosphat-hlcp-herstellverfahren-und-anwendung\/\" \/>\n<meta property=\"og:site_name\" content=\"EZN\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ezngmbh\/\" \/>\n<meta property=\"article:modified_time\" content=\"2022-11-28T12:45:53+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.ezn.de\/en\/ezn-patent\/kristallines-hybridschicht-dicalciumphosphat-hlcp-herstellverfahren-und-anwendung\/\",\"url\":\"https:\/\/www.ezn.de\/en\/ezn-patent\/kristallines-hybridschicht-dicalciumphosphat-hlcp-herstellverfahren-und-anwendung\/\",\"name\":\"Crystalline hybrid layer dicalcium phosphate (HLCP), production process and application | EZN\",\"isPartOf\":{\"@id\":\"https:\/\/www.ezn.de\/#website\"},\"datePublished\":\"2022-11-25T11:52:39+00:00\",\"dateModified\":\"2022-11-28T12:45:53+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.ezn.de\/en\/ezn-patent\/kristallines-hybridschicht-dicalciumphosphat-hlcp-herstellverfahren-und-anwendung\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.ezn.de\/en\/ezn-patent\/kristallines-hybridschicht-dicalciumphosphat-hlcp-herstellverfahren-und-anwendung\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.ezn.de\/en\/ezn-patent\/kristallines-hybridschicht-dicalciumphosphat-hlcp-herstellverfahren-und-anwendung\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.ezn.de\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Tech-Offer\",\"item\":\"https:\/\/www.ezn.de\/ezn-patent\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Crystalline hybrid layer dicalcium phosphate (HLCP), production process and application\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.ezn.de\/#website\",\"url\":\"https:\/\/www.ezn.de\/\",\"name\":\"EZN\",\"description\":\"WE GET IDEAS MOVING\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.ezn.de\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.ezn.de\/#\/schema\/person\/09871074ce7124f2c336b9ae90419d92\",\"name\":\"admin\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.ezn.de\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/09ddb5e9f1324c1f6ead75f6dde04c2611302f92a53bfcf6475d200adfa16a7c?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/09ddb5e9f1324c1f6ead75f6dde04c2611302f92a53bfcf6475d200adfa16a7c?s=96&d=mm&r=g\",\"caption\":\"admin\"},\"url\":\"https:\/\/www.ezn.de\/en\/author\/admin\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Crystalline hybrid layer dicalcium phosphate (HLCP), production process and application | EZN","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.ezn.de\/en\/ezn-patent\/kristallines-hybridschicht-dicalciumphosphat-hlcp-herstellverfahren-und-anwendung\/","og_locale":"en_US","og_type":"article","og_title":"Crystalline hybrid layer dicalcium phosphate (HLCP), production process and application | EZN","og_description":"Despite the broad potential and scope of application in bone tissue engineering, conventional CaP materials exhibit poor biodegradability, low load-bearing capacity, modest mechanical properties, and insufficient bioactivity or osteoinductivity, among others. These properties are detrimental to targeted drug delivery and sustained action and\/or controlled drug release. Porous CaP materials are useful for cell colonization, vascularization, […]","og_url":"https:\/\/www.ezn.de\/en\/ezn-patent\/kristallines-hybridschicht-dicalciumphosphat-hlcp-herstellverfahren-und-anwendung\/","og_site_name":"EZN","article_publisher":"https:\/\/www.facebook.com\/ezngmbh\/","article_modified_time":"2022-11-28T12:45:53+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.ezn.de\/en\/ezn-patent\/kristallines-hybridschicht-dicalciumphosphat-hlcp-herstellverfahren-und-anwendung\/","url":"https:\/\/www.ezn.de\/en\/ezn-patent\/kristallines-hybridschicht-dicalciumphosphat-hlcp-herstellverfahren-und-anwendung\/","name":"Crystalline hybrid layer dicalcium phosphate (HLCP), production process and application | EZN","isPartOf":{"@id":"https:\/\/www.ezn.de\/#website"},"datePublished":"2022-11-25T11:52:39+00:00","dateModified":"2022-11-28T12:45:53+00:00","breadcrumb":{"@id":"https:\/\/www.ezn.de\/en\/ezn-patent\/kristallines-hybridschicht-dicalciumphosphat-hlcp-herstellverfahren-und-anwendung\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.ezn.de\/en\/ezn-patent\/kristallines-hybridschicht-dicalciumphosphat-hlcp-herstellverfahren-und-anwendung\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.ezn.de\/en\/ezn-patent\/kristallines-hybridschicht-dicalciumphosphat-hlcp-herstellverfahren-und-anwendung\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.ezn.de\/en\/"},{"@type":"ListItem","position":2,"name":"Tech-Offer","item":"https:\/\/www.ezn.de\/ezn-patent\/"},{"@type":"ListItem","position":3,"name":"Crystalline hybrid layer dicalcium phosphate (HLCP), production process and application"}]},{"@type":"WebSite","@id":"https:\/\/www.ezn.de\/#website","url":"https:\/\/www.ezn.de\/","name":"EZN","description":"WE GET IDEAS MOVING","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.ezn.de\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.ezn.de\/#\/schema\/person\/09871074ce7124f2c336b9ae90419d92","name":"admin","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.ezn.de\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/09ddb5e9f1324c1f6ead75f6dde04c2611302f92a53bfcf6475d200adfa16a7c?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/09ddb5e9f1324c1f6ead75f6dde04c2611302f92a53bfcf6475d200adfa16a7c?s=96&d=mm&r=g","caption":"admin"},"url":"https:\/\/www.ezn.de\/en\/author\/admin\/"}]}},"ref-nr":"17212","summary":"Calcium phosphate (CaP) nanomaterials are of great importance as vehicles for e.g. antibiotics, growth factors or various drugs for the treatment of bone diseases, the promotion of hard tissue regeneration or the prevention of implant rejection, among others. The present innovation relates to a new crystalline hybrid layered dicalcium phosphate (HLCP) as a base material for, among others, bioceramics, biocomposites, bone scaffolds, implants and as a drug carrier. ","_links":{"self":[{"href":"https:\/\/www.ezn.de\/en\/wp-json\/wp\/v2\/ezn-patent\/7712","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ezn.de\/en\/wp-json\/wp\/v2\/ezn-patent"}],"about":[{"href":"https:\/\/www.ezn.de\/en\/wp-json\/wp\/v2\/types\/ezn-patent"}],"author":[{"embeddable":true,"href":"https:\/\/www.ezn.de\/en\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"href":"https:\/\/www.ezn.de\/en\/wp-json\/wp\/v2\/ezn-patent\/7712\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.ezn.de\/en\/wp-json\/wp\/v2\/media?parent=7712"}],"wp:term":[{"taxonomy":"ezn-category","embeddable":true,"href":"https:\/\/www.ezn.de\/en\/wp-json\/wp\/v2\/ezn-category?post=7712"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}